Unified control software for FIB-SEM microscopy
Open-source platform unifying microscope drivers, automating complex workflows, and enabling reproducible cryo-electron tomography sample preparation.
Unified Drivers
Single API for Thermo Fisher, ZEISS, and TESCAN instruments.
Automated Workflows
Built-in support for on-grid lamella, waffle milling, and custom workflows.
3D Correlation
Correlate fluorescence and electron microscopy data for targeted prep.
Light Microscope Integration
Control in-chamber fluorescence microscopes for correlative workflows.
Data Management
Automatic organization and metadata tracking for reproducible science.
User Friendly UI
Modern interface tailored to the imaging ecosystem.
Community
Australia
Austria
Australia
Germany
Germany
Germany
Germany
Germany
USA
USA
Australia
Austria
Related Publications
2025
Reduction of SEM charging artefacts in native cryogenic biological samplesNature CommunicationsNature Communications
2025
Mind the corner: Fillets in cryo-FIB lamella preparation to minimise sample lossJournal of Structural BiologyJournal of Structural Biology
2023
OpenFIBSEM: A universal API for FIBSEM controlJournal of Structural BiologyJournal of Structural Biology
2020
Automated cryo-lamella preparation for high-throughput in-situ structural biologyJournal of Structural BiologyJournal of Structural Biology
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