Unified control software for FIB-SEM microscopy
Open-source platform unifying microscope drivers, automating complex workflows, and enabling reproducible cryo-electron tomography sample preparation.
Unified Drivers
Single API for Thermo Fisher, ZEISS, and TESCAN instruments.
Automated Workflows
Built-in support for on-grid lamella, waffle milling, and custom workflows.
3D Correlation
Correlate fluorescence and electron microscopy data for targeted prep.
Light Microscope Integration
Control in-chamber fluorescence microscopes for correlative workflows.
Data Management
Automatic organization and metadata tracking for reproducible science.
User Friendly UI
Modern interface tailored to the imaging ecosystem.
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Related Publications
2025
Reduction of SEM charging artefacts in native cryogenic biological samplesNature CommunicationsNature Communications
2025
Mind the corner: Fillets in cryo-FIB lamella preparation to minimise sample lossJournal of Structural BiologyJournal of Structural Biology
2023
OpenFIBSEM: A universal API for FIBSEM controlJournal of Structural BiologyJournal of Structural Biology
2020
Automated cryo-lamella preparation for high-throughput in-situ structural biologyJournal of Structural BiologyJournal of Structural Biology
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